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Nalfurafine, a G-Protein–Biased KOR (Kappa Opioid Receptor) Agonist,  Enhances the Diuretic Response and Limits Electrolyte Losses to  Standard-of-Care Diuretics | Hypertension
Nalfurafine, a G-Protein–Biased KOR (Kappa Opioid Receptor) Agonist, Enhances the Diuretic Response and Limits Electrolyte Losses to Standard-of-Care Diuretics | Hypertension

Putative interaction modes of morphine-based high-affinity... | Download  Scientific Diagram
Putative interaction modes of morphine-based high-affinity... | Download Scientific Diagram

The receptor hypothesis and the pathogenesis of depression: Genetic bases  and biological correlates - ScienceDirect
The receptor hypothesis and the pathogenesis of depression: Genetic bases and biological correlates - ScienceDirect

κ-opioid receptor - Wikipedia
κ-opioid receptor - Wikipedia

Lion's Mane contains kappa agonist - Supplements - LONGECITY
Lion's Mane contains kappa agonist - Supplements - LONGECITY

Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico  Characterization of a Novel Kappa-Opioid Receptor Antagonist
Pharmaceuticals | Free Full-Text | In Vitro, In Vivo and In Silico Characterization of a Novel Kappa-Opioid Receptor Antagonist

A Phase 3 Trial of Difelikefalin in Hemodialysis Patients with Pruritus |  NEJM
A Phase 3 Trial of Difelikefalin in Hemodialysis Patients with Pruritus | NEJM

Antagonists of the kappa opioid receptor - ScienceDirect
Antagonists of the kappa opioid receptor - ScienceDirect

Frontiers | The role of endogenous opioid neuropeptides in  neurostimulation-driven analgesia
Frontiers | The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia

Molecules | Free Full-Text | Mechanistic Characterization of the  Pharmacological Profile of HS-731, a Peripherally Acting Opioid Analgesic,  at the µ-, δ-, κ-Opioid and Nociceptin Receptors
Molecules | Free Full-Text | Mechanistic Characterization of the Pharmacological Profile of HS-731, a Peripherally Acting Opioid Analgesic, at the µ-, δ-, κ-Opioid and Nociceptin Receptors

Structural Assessment of Agonist Efficacy in the μ-Opioid Receptor:  Morphine and Fentanyl Elicit Different Activation Patterns | Journal of  Chemical Information and Modeling
Structural Assessment of Agonist Efficacy in the μ-Opioid Receptor: Morphine and Fentanyl Elicit Different Activation Patterns | Journal of Chemical Information and Modeling

I'll Be Back”: The Resurrection of Dezocine | ACS Medicinal Chemistry  Letters
I'll Be Back”: The Resurrection of Dezocine | ACS Medicinal Chemistry Letters

Antagonists of the kappa opioid receptor - ScienceDirect
Antagonists of the kappa opioid receptor - ScienceDirect

Synthesis and Structure–Activity Relationships of  5′-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor  Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive  Activity and Diminished Opioid Side Effects | Journal ...
Synthesis and Structure–Activity Relationships of 5′-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects | Journal ...

The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology  of Schizophrenia: A Review of the Evidence
The Role of Dynorphin and the Kappa Opioid Receptor in the Symptomatology of Schizophrenia: A Review of the Evidence

6,5‐Fused Ring, C2‐Salvinorin Ester, Dual Kappa and Mu Opioid Receptor  Agonists as Analgesics Devoid of Anxiogenic Effects** - Akins - 2022 -  ChemMedChem - Wiley Online Library
6,5‐Fused Ring, C2‐Salvinorin Ester, Dual Kappa and Mu Opioid Receptor Agonists as Analgesics Devoid of Anxiogenic Effects** - Akins - 2022 - ChemMedChem - Wiley Online Library

Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist  Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical  Neuroscience
Discovery of Small Molecule Kappa Opioid Receptor Agonist and Antagonist Chemotypes through a HTS and Hit Refinement Strategy | ACS Chemical Neuroscience

IJMS | Free Full-Text | Dendritic Cells and Their Immunotherapeutic  Potential for Treating Type 1 Diabetes
IJMS | Free Full-Text | Dendritic Cells and Their Immunotherapeutic Potential for Treating Type 1 Diabetes

Frontiers | Crosstalk Between Kappa Opioid and Dopamine Systems in  Compulsive Behaviors
Frontiers | Crosstalk Between Kappa Opioid and Dopamine Systems in Compulsive Behaviors

Role of RGS12 in the differential regulation of kappa opioid  receptor-dependent signaling and behavior | Neuropsychopharmacology
Role of RGS12 in the differential regulation of kappa opioid receptor-dependent signaling and behavior | Neuropsychopharmacology

Preventing Morphine-Seeking Behavior through the Re-Engineering of  Vincamine's Biological Activity | Journal of Medicinal Chemistry
Preventing Morphine-Seeking Behavior through the Re-Engineering of Vincamine's Biological Activity | Journal of Medicinal Chemistry

Frontiers | Advances in Achieving Opioid Analgesia Without Side Effects
Frontiers | Advances in Achieving Opioid Analgesia Without Side Effects

Kappa Opioid Receptor Activation Potentiates the Cocaine-Induced Increase  in Evoked Dopamine Release Recorded In Vivo in the Mouse Nucleus Accumbens  | Neuropsychopharmacology
Kappa Opioid Receptor Activation Potentiates the Cocaine-Induced Increase in Evoked Dopamine Release Recorded In Vivo in the Mouse Nucleus Accumbens | Neuropsychopharmacology

Nanobody-enabled monitoring of kappa opioid receptor states | Nature  Communications
Nanobody-enabled monitoring of kappa opioid receptor states | Nature Communications

Ethanol and Naltrexone Have Distinct Effects on the Lateral  Nano-organization of Mu and Kappa Opioid Receptors in the Plasma Membrane |  ACS Chemical Neuroscience
Ethanol and Naltrexone Have Distinct Effects on the Lateral Nano-organization of Mu and Kappa Opioid Receptors in the Plasma Membrane | ACS Chemical Neuroscience

Prefrontal Cortical Kappa-Opioid Receptor Modulation of Local  Neurotransmission and Conditioned Place Aversion | Neuropsychopharmacology
Prefrontal Cortical Kappa-Opioid Receptor Modulation of Local Neurotransmission and Conditioned Place Aversion | Neuropsychopharmacology

Dynamic lateral organization of opioid receptors (kappa, muwt and muN40D)  in the plasma membrane at the nanoscale level - Rogacki - 2018 - Traffic -  Wiley Online Library
Dynamic lateral organization of opioid receptors (kappa, muwt and muN40D) in the plasma membrane at the nanoscale level - Rogacki - 2018 - Traffic - Wiley Online Library

Pharmaceuticals | Free Full-Text | Opioid Analgesia and Opioid-Induced  Adverse Effects: A Review
Pharmaceuticals | Free Full-Text | Opioid Analgesia and Opioid-Induced Adverse Effects: A Review